The most successful core build consists of Rod of Ages, Archangel's Staff, and Zhonya's Hourglass, which boasts a high 60.8% win rate. You should pair these with Sorcerer's Shoes and start your lane with Doran's Ring and two Health Potions. This setup provides significantly better results than the alternative Liandry's Torment path.

The optimal rune page uses Electrocute as the primary keystone from the Domination tree, alongside Cheap Shot, Grisly Mementos, and Relentless Hunter. For your secondary tree, take Precision with Coup de Grace and Presence of Mind. This specific configuration currently maintains a 51.1% win rate across 25.9% of games.

Anivia is currently ranked as a B tier champion in the Mid lane for patch 16.2.1. With a win rate of 48.3% and a carry score of 5.7 out of 10, she is a balanced but challenging pick. She is not considered a top-tier dominant champion in the current meta.

Anivia's general win rate in the Mid lane is 48.3% based on an analysis of 1523 games. However, players who use her build-specific core items see a slightly higher win rate of 49.9%. Expert players using the Zhonya's Hourglass variant can reach win rates as high as 60.8%.

Since the data provided is from Platinum+ games where she has a 48.3% win rate, she may be difficult to pilot in lower ranks. Given her 10 out of 10 difficulty rating, she requires high mechanical skill to be effective. Players in low elo might struggle with her complex kit compared to simpler mages.

Anivia is a high-reward champion for those who can master her 10 out of 10 difficulty, as seen by the 60.8% win rate on specific core builds. While her overall win rate is 48.3%, her carry score of 5.7 indicates she can impact games significantly when played well. She is a solid choice if you enjoy complex mages and are willing to invest the time to learn her.

Her win rate of 48.3% is on the lower side because she is a high-difficulty champion that requires precise execution. The current meta places her in B tier, suggesting she may struggle against more dominant mid-lane picks. Her success is heavily dependent on itemization, with some builds performing much better than others.

Malignance is the best first item for Anivia, yielding a 53.1% win rate over 179 games. It outperforms her average win rate and provides a strong early power spike for her kit. Choosing this over other options can help stabilize her 48.3% overall win rate during the early stages of the match.

You should pick Anivia when you have mastered her 10/10 difficulty and can utilize her E > Q > W skill max order effectively. She is a reliable B tier pick if you can reach her core items like Rod of Ages and Archangel's Staff. She is best picked when you can afford to scale, as her late-game item builds show much higher success rates.

Anivia's first major power spike occurs when she completes Malignance, which carries a 53.1% win rate. As the game progresses, her three-item spike of Rod of Ages, Archangel's Staff, and Zhonya's Hourglass is exceptionally strong at 60.8%. You should play conservatively early and focus on reaching these item milestones while maximizing your E damage.

Anivia is strongest in the mid to late game once she has completed her core items and leveled her E and Q abilities. Her win rate jumps from 48.3% to over 60% once she has three items like Zhonya's Hourglass. Her early game is more about survival and scaling, as indicated by her starting items and high difficulty rating.

Anivia received no direct champion changes in patch 16.2.1. Additionally, there were no changes to her core items or runes in this update. Her performance remains consistent with her B tier status and 48.3% win rate from previous data.

The Electrocute and Precision combination is the standard recommended setup with a 51.1% win rate. While the data does not provide alternative runes, this specific page is optimized for burst damage with Cheap Shot and Coup de Grace. It is generally the most reliable choice for Anivia across various matchups in the Mid lane.